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Three-dimensional radiation dosimetry of carbon ion beams using surfactant hydrogels: Fundamental investigation
http://hdl.handle.net/10131/0002001353
http://hdl.handle.net/10131/000200135391481cb2-41ca-4019-aabc-c47f6ac95199
| 名前 / ファイル | ライセンス | アクション |
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Medical Physics - 2024 - Toyohara - Three‐dimensional radiation dosimetry of carbon ion beams using surfactant hydrogels .pdf (3.2 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| 公開日 | 2024-10-22 | |||||||||||||
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| タイトル | Three-dimensional radiation dosimetry of carbon ion beams using surfactant hydrogels: Fundamental investigation | |||||||||||||
| 言語 | en | |||||||||||||
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| 言語 | eng | |||||||||||||
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| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| アクセス権 | ||||||||||||||
| アクセス権 | open access | |||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||
| 著者 |
Toyohara, Masumitsu
× Toyohara, Masumitsu
× Kusano, Yohsuke× Kobayashi, Norihisa
× Gotoh, Hiroaki
e-Rad_Researcher
80635235
× Wada, Satoshi
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| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Background In carbon ion radiotherapy, accurate measurement of the three-dimensional (3D) absorbed dose distribution is critical for effectively targeting tumors. Although micellar gel dosimeters exhibit considerable potential for measuring 3D absorbed dose distributions, few studies have focused on radiotherapy using carbon ion beams. Purpose This study investigated the applicability of the surfactant hydrogel dosimeter (SHD), a micellar gel dosimeter, to measuring a 3D dose absorbed through carbon ion beam irradiation. Methods A cubic target region of 34 mm per side was established at a depth of 46 mm below the upper surface of an SHD specimen. Scanning irradiation was performed using a pencil beam of carbon ions at the Ion-beam Radiation Oncology Center in Kanagawa (“i-ROCK”), Japan, under irradiation conditions set by the treatment planning system (“Monaco for Carbon”, Ver. 5.20, Elekta AB, Sweden) to create a spread-out Bragg peak within the target. The physical dose was set to 10 Gy at the isocenter, situated at the center of the target. The SHD responsiveness was measured twice using optical computed tomography (CT) (“Vista 15”, Modus Medical Devices, Canada) for three irradiated specimens, and six types of measured optical attenuation coefficient (OAC) were obtained. To assess whether the OAC represented the absorbed dose expected in the treatment plan, we compared the relative distribution of the OAC and that of the absorbed dose. Relative fraction (RF) was used to measure the difference between the relative value of the OAC and that of the absorbed dose. Moreover, the distribution of OH radical (•OH) concentration obtained by Monte Carlo simulation (“PHITS” ver. 3.24 JAEA, Japan) and that of the OAC were compared. Results In the direction of beam travel, the relative distribution of the OAC was lower than that of the absorbed dose. This discrepancy could be attributed to a decrease in the concentration of •OH produced by irradiation owing to the recombination reaction, which does not accurately reflect the absorbed dose. By contrast, the distributions in the plane perpendicular to the beam travel were consistent. The RF increased from ± 3% to ± 13% along the beam travel direction. The small RF in the plane perpendicular to the beam travel could be attributed to the constant distribution of linear energy transfer, regardless of the irradiation position, and the generation of radicals proportionally to the absorbed dose. The increase in RF along the beam travel direction was ascribed to ring artifacts in the irradiated region. Conclusion The measurement of the absorbed dose distribution in the beam travel direction should be improved. The observed discrepancy is attributed to the reduced reactivity of the SHD due to a high liner energy transfer near the Bragg peak. However, the absorbed dose distribution can be effectively evaluated in the plane perpendicular to the direction of beam travel. |
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| 言語 | en | |||||||||||||
| 書誌情報 |
en : Medical Physics 巻 Early Access, ページ数 17, 発行日 2024-10-09 |
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| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 00942405 | |||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA00727671 | |||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.1002/mp.17433 | |||||||||||||
| 権利 | ||||||||||||||
| 言語 | en | |||||||||||||
| 権利情報Resource | https://creativecommons.org/licenses/by-nc/4.0/ | |||||||||||||
| 権利情報 | Creative Commons Attribution-NonCommercial 4.0 International | |||||||||||||
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| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
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| 出版者 | American Association of Physicists in Medicine | |||||||||||||
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| 出版者 | Wiley | |||||||||||||
